This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells ...

Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into a suppressed state. This previously unrecognized molecular interaction, ...

AT-108 induces powerful, personalized anti-cancer responses by forcing tumor cells to present their antigens to the immune ...

Add Yahoo as a preferred source to see more of our stories on Google. A Nature Immunology study suggests PARP inhibitors can reprogram CD8 T cells into longer-lasting “superior memory” cancer fighters ...

Why pluripotent stem cells are worth the race The urgency around faster reprogramming is not just about lab convenience, it is about unlocking what pluripotent stem cells can actually do. Human ...

Researchers at Oregon Health & Science University have uncovered a key reason why immunotherapy has largely failed in pancreatic cancer—and identified a promising strategy to overcome that resistance.

A new way of reprogramming our immune cells to shrink or kill off cancer cells has been shown to work in the otherwise hard to treat and devastating skin cancer, melanoma. The University of ...

Parvalbumin (PV) interneurons act as the brain’s rhythm keepers. By regulating local circuit activity and maintaining excitation–inhibition balance, they help stabilize cortical network function. When ...

Researchers created hybrid macrophages that support multiple stages of bone healing, including regeneration and ...